Error Interacting with configuration file while running ESXCLI

Problem: This error when running esxcli command

Error interacting with configuration file /etc/vmware/lunTimestamps.log: Timeout while waiting for lock, /etc/vmware/lunTimestamps.log.LOCK, to be released. Another process has kept this file locked for more than 20-30 seconds. The process currently holding the lock is smartd(PID). This is likely a temporary condition. Please try your operation again

ESXi host showing as Disconnected in vCenter Server is a known issue in ESXi 6.0.

Solution

This is a known issue affecting ESXi 6.0.  Currently, there is no resolution.

To work around this issue, disable smartd daemon on the host.

To disable smartd daemon:

1. Connect to the affected ESXi host with an SSH session.
2. Run this command to stop the smartd service:
   
   /etc/init.d/smartd stop
   
   
3. Run this command to stop the smartd service from starting on reboot:
   
   chkconfig smartd off